Glial cell induced neural differentiation of bone marrow stromal cells
Background: Bone marrow stromal cells (BMSCs) have an necessary utility prospect within the area of cell remedy for varied neurodegenerative ailments, and inducing components that regulate BMSC differentiation are proposed as a promising therapeutic technique. On this examine, we explored the impact of glial cell-derived neurotrophic issue (GDNF) on the course of BMSC differentiation.
Strategies: BMSCs have been remoted from rat bone marrow and induced by GDNF. The results of GDNF on BMSC viability and proliferation have been verified by cell counting equipment-8, MTT, bromodeoxyuridine, and move cytometry assays. Neuronal differentiation from BMSCs was detected by quantitative real-time polymerase chain response and immunofluorescence through measuring the expression of a number of neural particular markers.
Outcomes: In comparison with untreated BMSCs, GDNF induced the differentiation of BMSCs into neuron-like cells and enhanced the expression ranges of neuronal markers together with nestin and NCAM. Furthermore, the expression of SCF was suppressed by GDNF stimulation.
Conclusion: GDNF may elevate the differentiation of BMSCs into neuron-like cells and may very well be thought-about as an efficient candidate cell for future neuroscience analysis.
Key phrases: Alzheimer’s illness; bone marrow stromal cells; cell remedy; glial cell-derived neurotrophic issue; neuronal differentiation.

Molecular detection of Mycobacterium tuberculosis from buccal swabs amongst grownup in Peru

Tuberculosis (TB) prognosis depends on a sputum pattern, which can’t be simply obtained from all symptomatic sufferers. Mycobacterium tuberculosis DNA will be detected from oral swabs, a noninvasive, protected different pattern sort; nonetheless, reported sensitivities have been variable and sure rely upon pattern assortment, processing procedures and host traits. We analyzed three buccal swab samples from 123 adults with culture-confirmed TB in Lima, Peru. We in contrast the sensitivity and specificity of two pattern assortment units (OmniSwab and EasiCollect FTA playing cards) and examined components related to detection. DNA was extracted with a commercially out there equipment and detected through real-time PCR IS6110 amplification.
General sensitivity for buccal samples was 51% (95% Confidence Interval [CI] 42-60%). Specificity from a single pattern amongst wholesome controls was 96.7% (95% CI 83-99.9%). Optimistic sputum smear and cavitary illness, correlates of illness burden, have been related to detection through buccal swab. Though we noticed greater sensitivities with the Omniswab samples, this gave the impression to be due primarily to variations in affected person traits (e.g., cavitary illness). General, our findings assist the potential for a buccal sample-based TB assay. Future work ought to concentrate on assay optimization and streamlining the assay workflow.
Our outcomes confirmed that SSa pretreatment may considerably scale back mind harm, enhance neurological operate restoration, and reduce the water content material of mind tissues in comparison with the mannequin group. SSa pretreatment considerably lowered the serum HMGB1 degree and downregulated the contents of inflammatory cytokines together with tumor necrosis factor-α, interleukin-1 beta, and interleukin-6. Moreover, SSa pretreatment may attenuate the decreased TLR4 and nucleus NF-κB within the mind of MCAO rats. The protein degree of HMGB1 within the nucleus was considerably upregulated within the SSa pretreatment group.
We ready CDDP/CQ-PLA NPs and CDDP-PLA NPs. Transmission electron microscope (TEM) and dynamic gentle scattering (DLS) have been used to detect the physiological traits and particle dimension parameters of drug-loaded nanoparticles. The drug focus and cumulative launch have been measured by UV and visual spectrophotometer. MTT assay was used to detect viability of Cal-27 cells. Annexin/PI staining was used to detect cell apoptosis. Organic kits have been used to detect malondialdehyde (MDA) content material, catalase (CAT) exercise, antioxidant enzyme superoxide dismutase (SOD) exercise and glutathione peroxidase (GSH PX) exercise in Cal-27 cells. Western blot was used to detect apoptosis and autophagy of Cal-27 cells.
 Glial cell induced neural differentiation of bone marrow stromal cells

Glial cell induced neural differentiation of bone marrow stromal cells

Salivary Carbohydrate-Poor Transferrin in Alcohol- and Nicotine-Dependent Males

Serum carbohydrate-deficient transferrin (CDT), an 80 kDa glycoprotein, is among the mostly employed biomarkers to detect alcohol dependence. Some salivary glycoproteins comparable to α-amylase, clusterin, haptoglobin, gentle/heavy-chain immunoglobulin, and transferrin, which alter glycosylation in alcohol-dependent individuals, have been recommended to be potential alcohol markers. Nevertheless, their identification is predicated on oblique evaluation of lectin glycosidic bonds and molecular weight. We investigated the CDT content material within the saliva of alcohol- and nicotine-dependent males.
The CDT focus (ng/mL, ng/mg protein) was decided by an Enzyme-Linked Immunosorbent Assay (ELISA) industrial equipment in 55 males: 20 wholesome social drinkers (C), 10 power cigarette people who smoke (S), 10 alcohol-dependent non-smokers (A), and 15 alcohol-dependent people who smoke (AS). Surprisingly, there have been no variations within the concentrations of CDT between the studied teams. Salivary pH was the bottom within the AS and the best within the A gaggle. Subsequently, salivary CDT can’t be used as an alcohol dependence marker as measured by ELISA. We recommend that direct identification of glycoproteins is important to seek for potential salivary alcohol biomarkers. Molecules smaller than 40 kDa, which simply translocate from blood to the saliva, could be most popular as salivary alcohol markers.

TAGAP Recombinant Protein (Human) (Recombinant- Tag)

RP030880 100 ug Ask for price

TAGLN Recombinant Protein (Human) (Recombinant- Tag)

RP030883 100 ug Ask for price

TAGLN Recombinant Protein (Human) (Recombinant- Tag)

RP030886 100 ug Ask for price

Tagap1 Recombinant Protein (Mouse) (Recombinant Tag)

RP177158 100 ug Ask for price

TAGLN2 Recombinant Protein (Mouse) (Recombinant Tag)

RP177164 100 ug Ask for price

TAGLN3 Recombinant Protein (Mouse) (Recombinant Tag)

RP177167 100 ug Ask for price

CTAGE1 Recombinant Protein (Human) (Recombinant- Tag)

RP008266 100 ug Ask for price

CTAGE5 Recombinant Protein (Human) (Recombinant- Tag)

RP008269 100 ug Ask for price

CTAGEP Recombinant Protein (Human) (Recombinant- Tag)

RP008275 100 ug Ask for price

CTAGE5 Recombinant Protein (Mouse) (Recombinant- Tag)

RP126449 100 ug Ask for price

CTAGE5 Recombinant Protein (Mouse) (Recombinant- Tag)

RP126452 100 ug Ask for price

CTAGE5 Recombinant Protein (Mouse) (Recombinant- Tag)

RP126455 100 ug Ask for price

CTAGE4 Recombinant Protein (Human) (Recombinant- Tag)

RP053403 100 ug Ask for price

CTAGE8 Recombinant Protein (Human) (Recombinant- Tag)

RP053409 100 ug Ask for price

CTAGE9 Recombinant Protein (Human) (Recombinant- Tag)

RP053412 100 ug Ask for price

CTAG1A Recombinant Protein (Human) (Recombinant- Tag)

RP038332 100 ug Ask for price

CTAG1B Recombinant Protein (Human) (Recombinant- Tag)

RP038335 100 ug Ask for price

CTAGE5 Recombinant Protein (Human) (Recombinant- Tag)

RP038338 100 ug Ask for price

TAGLN2 Recombinant Protein (Human) (Recombinant Tag)

RP030889 100 ug Ask for price

TAGLN2 Recombinant Protein (Human) (Recombinant Tag)

RP030892 100 ug Ask for price

TAGLN3 Recombinant Protein (Human) (Recombinant Tag)

RP030895 100 ug Ask for price

Glyco Recombinant Protein A33 Recombinant Protein

96-361 0.05 mg
EUR 619.8
Description: Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.

Glyco Recombinant Protein A33 Recombinant Protein

96-364 0.05 mg
EUR 619.8
Description: Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.

CTAGE6P Recombinant Protein (Human) (Recombinant Tag)

RP008272 100 ug Ask for price

CTAGE3P Recombinant Protein (Human) (Recombinant Tag)

RP053400 100 ug Ask for price

STAG3L1 Recombinant Protein (Human) (Recombinant Tag)

RP030283 100 ug Ask for price

STAG3L2 Recombinant Protein (Human) (Recombinant Tag)

RP030286 100 ug Ask for price

STAG3L3 Recombinant Protein (Human) (Recombinant Tag)

RP030289 100 ug Ask for price

STAG3L4 Recombinant Protein (Human) (Recombinant Tag)

RP030292 100 ug Ask for price

CTAG2 Recombinant Protein (Rat) (Recombinant-P Tag)

RP196619 100 ug Ask for price

CTAG2 Recombinant Protein (Mouse) (Recombinant-P Tag)

RP126446 100 ug Ask for price

CTAG2 Recombinant Protein (Human) (Recombinant-P Tag)

RP053376 100 ug Ask for price

Recombinant Rat Apoliprotein-J (Clusterin Rat Recombinant)

CC015-002 2ug
EUR 351.6

Recombinant Rat Apoliprotein-J (Clusterin Rat Recombinant)

CC015-010 10ug
EUR 489.6

Recombinant Rat Apoliprotein-J (Clusterin Rat Recombinant)

CC015-101 1mg
EUR 8322

HSA Recombinant, Human Serum Albumin Recombinant Protein, HEK

PROTP02768-2 Regular: 100ug
EUR 380.4
Description: Recombinant Human Serum Albumin produced in HEK cells is a glycosylated monomer, having a molecular weight range of 60-65kDa due to glycosylation.;The HSA is purified by proprietary chromatographic techniques.

Recombinant phosphopantetheine adenylyltransferase (PPAT) (Recombinant)

20-abx072018
  • EUR 2230.80
  • EUR 1095.60
  • EUR 393.60
  • 1 mg
  • 300 µg
  • 50 ug

Recombinant Human Apoliprotein-J (Clusterin Human Recombinant)

CC014-002 2ug
EUR 351.6

Recombinant Human Apoliprotein-J (Clusterin Human Recombinant)

CC014-010 10ug
EUR 489.6

Recombinant Human Apoliprotein-J (Clusterin Human Recombinant)

CC014-101 1mg
EUR 13344

HSA Recombinant, Human Serum Albumin Recombinant Protein, Plant

PROTP02768-1 Regular: 50mg
EUR 565.2
Description: HSA Human Recombinant produced in Plant is a non-glycosylated, polypeptide chain containing 585 amino acids and having a molecular mass of 67 kDa.The optimum concentration for recombinant Albumin to be used in cell culture ranges between 0.5gr to 2gr per liter3.;The recombinant Albumin is purified by proprietary chromatographic techniques.

Recombinant RFP

STA-202 100 ?g
EUR 470.4
Description:
  • Recombinant RFP contains a 6x-His tag at the C-terminus. Provided as 100 µg/vial at a concentration of 1 mg/mL.
  • Includes 6xHis-tag at C-terminus
  • Provided at 100 ?g/vial at 1.0 mg/mL in 1X PBS
  • Recombinant Protein purified from E. coli

Recombinant RFP

STA-202-5 5 x 100 µg
EUR 1681.2
Description:
  • Recombinant RFP contains a 6x-His tag at the C-terminus. Provided as 5 vials of 100 µg at a concentration of 1 mg/mL.
  • Includes 6xHis-tag at C-terminus
  • Provided at 100 ?g/vial at 1.0 mg/mL in 1X PBS
  • Recombinant Protein purified from E. coli

Recombinant 5T4

RPU53907-100ug 100ug
EUR 566.5

Recombinant 5T4

RPU53907-1mg 1mg
EUR 2511.6

Recombinant 5T4

RPU53907-50ug 50ug
EUR 455.4

Recombinant 5T4

RPU54319-100ug 100ug
EUR 591.8

Recombinant 5T4

RPU54319-1mg 1mg
EUR 2620.8

Recombinant 5T4

RPU54319-50ug 50ug
EUR 475.2

Recombinant other HSA Recombinant Protein, Untagged, Rice-10mg

QP12317-10mg 10mg
EUR 195.6

Recombinant other HSA Recombinant Protein, Untagged, Rice-20ug

QP12317-20ug 20ug
EUR 186

Recombinant other HSA Recombinant Protein, Untagged, Rice-50mg

QP12317-50mg 50mg
EUR 435.6

Recombinant other HSA Recombinant Protein, Untagged, Rice-100mg

QP12317-100mg 100mg
EUR 675.6

Recombinant other HSA Recombinant Protein, Untagged, HEK 293-100ug

QP12317-100ug 100ug
EUR 241.2

Recombinant other HSA Recombinant Protein, Untagged, HEK 293-2mg

QP12317-2mg 2mg
EUR 1513.2

YOD1 (Recombinant)

20-abx073982
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

NAT6 (Recombinant)

20-abx073034
  • EUR 727.20
  • EUR 460.80
  • EUR 560.40
  • 10 ug
  • 2 µg
  • 5 ug

GALE (Recombinant)

20-abx073137
  • EUR 3433.20
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

ADSL (Recombinant)

20-abx073250
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

MPST (Recombinant)

20-abx073378
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

TDP1 (Recombinant)

20-abx073385
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

MMP1 (Recombinant)

20-abx073422
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

ADAL (Recombinant)

20-abx073435
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

ACY1 (Recombinant)

20-abx073654
  • EUR 393.60
  • EUR 7108.80
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

TDO2 (Recombinant)

20-abx073952
  • EUR 276.00
  • EUR 1930.80
  • EUR 393.60
  • 1 µg
  • 50 ug
  • 5 ug

Recombinant EGFP

STA-201 100 ?g
EUR 470.4
Description:
  • Recombinant EGFP contains a 6x-His tag at the C-terminus. Provided as 100 µg/vial at a concentration of 1 mg/mL.
  • Includes 6xHis-tag at C-terminus
  • Provided at 100 ?g/vial at 1.0 mg/mL in 1X PBS
  • Recombinant Protein purified from E. coli

Recombinant EGFP

STA-201-5 5 x 100 µg
EUR 1681.2
Description:
  • Recombinant EGFP contains a 6x-His tag at the C-terminus. Provided as 5 vials of 100 µg at a concentration of 1 mg/mL.
  • Includes 6xHis-tag at C-terminus
  • Provided at 100 ?g/vial at 1.0 mg/mL in 1X PBS
  • Recombinant Protein purified from E. coli

ACAA2 (Recombinant)

20-abx073818
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

ADAT1 (Recombinant)

20-abx073911
  • EUR 393.60
  • EUR 9447.60
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Recombinant LukAB

0510-001 100ug
EUR 486
Description:
  • Related to: Staphylococcus
  • Applications: ELISA, WB

HTRA2 (Recombinant)

20-abx073047
  • EUR 276.00
  • EUR 2798.40
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

ACOT7 (Recombinant)

20-abx073258
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

ACAA1 (Recombinant)

20-abx073272
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

ADPRH (Recombinant)

20-abx073354
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

SMUG1 (Recombinant)

20-abx073377
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

MMP10 (Recombinant)

20-abx073421
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

ADAT2 (Recombinant)

20-abx073661
  • EUR 393.60
  • EUR 7108.80
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

APEX1 (Recombinant)

20-abx073692
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Urease (Recombinant)

20-abx073924
  • EUR 276.00
  • EUR 1612.80
  • EUR 393.60
  • 1 mg
  • 50 mg
  • 5 mg

Klotho (Recombinant)

20-abx073512
  • EUR 4519.20
  • EUR 393.60
  • EUR 276.00
  • 0.5 mg
  • 20 ug
  • 5 ug

Recombinant Urease

7-03790 1mg Ask for price

Recombinant Urease

7-03791 5mg Ask for price

Recombinant Urease

7-03792 50mg Ask for price

Urease (Recombinant)

22060744-1 1 mg
EUR 146.42

NDUFAF2 (Recombinant)

20-abx073714
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Latexin (Recombinant)

20-abx073558
  • EUR 5388.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

NDUFAF1 (Recombinant)

20-abx073578
  • EUR 5388.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

NDUFAF4 (Recombinant)

20-abx073976
  • EUR 276.00
  • EUR 1930.80
  • EUR 393.60
  • 1 µg
  • 50 ug
  • 5 ug

Recombinant Hirudin

7-05344 2µg Ask for price

Recombinant Hirudin

7-05345 10µg Ask for price

Recombinant Hirudin

7-05346 1mg Ask for price

Uricase, Recombinant

DIA-294 5KU
EUR 453.6

Recombinant Hirudin

TPOPP-0801 10ug Ask for price

AASDHPPT (Recombinant)

20-abx073160
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Gankyrin (Recombinant)

20-abx073293
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Catalase (Recombinant)

20-abx073353
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

PAFAH1B3 (Recombinant)

20-abx073360
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Renalase (Recombinant)

20-abx073367
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Protease (Recombinant)

abx073528-1000IU 1.000 IU
EUR 777.6

Protease (Recombinant)

abx073528-150IU 150 IU
EUR 393.6

Protease (Recombinant)

abx073528-50IU 50 IU
EUR 276

Recombinant Protease

7-03484 50IU Ask for price

Recombinant Protease

7-03485 150IU Ask for price

Recombinant Protease

7-03486 1,000IU Ask for price

Recombinant Asprosin

RPU58647-100ug 100ug
EUR 604.8

Recombinant Asprosin

RPU58647-1mg 1mg
EUR 2808

Recombinant Asprosin

RPU58647-50ug 50ug
EUR 470.3

EGF, rat recombinant

4024-100 each
EUR 364.8

EGF, rat recombinant

4024-1000 each
EUR 2173.2

EGF, rat recombinant

4024-20 each
EUR 192

SCF, rat recombinant

4329-10 each
EUR 398.4

SCF, rat recombinant

4329-1000 each
EUR 5136

SCF, rat recombinant

4329-50 each
EUR 946.8

TPO, rat recombinant

7221-10 each
EUR 301.2

TPO, rat recombinant

7221-50 each
EUR 1136.4

Recombinant SIV p55

7-07750 2µg Ask for price

Recombinant SIV p55

7-07751 10µg Ask for price

Recombinant SIV p55

7-07752 100µg Ask for price

Recombinant EBV p18

DAGA-3074 100ug
EUR 1279.2

Recombinant Rat Phb

P1465 100ug Ask for price
Description: Recombinant protein for Rat Phb

SIV p55 (Recombinant)

22060697-1 2 µg
EUR 146.42

C-JUN (Recombinant)

22060034-1 2 µg
EUR 146.42

Recombinant Rat EGF

REGFP-0501 100ug Ask for price

Recombinant Rat LIF

REOPP-1201 5ug Ask for price

Recombinant Rat MIF

REOPP-1303 10ug Ask for price

Recombinant Rat OSM

REOPP-1501 10ug Ask for price

Recombinant Rat SCF

REOPP-1902 10ug Ask for price

Recombinant MIP-2

VEOPP-2202 10ug Ask for price

Recombinant Rat EGF

Z300045 100 µg
EUR 120
Description: Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. This protein shows both strong sequential and functional homology with human type-alpha transforming growth factor (hTGF alpha), which is a competitor for EGF receptor sites. EGF receptors are expressed in almost all types of tissues. Parietal endoderm, mature skeletal muscles, and hematopoietic tissues do not express the receptor. The EGF receptor, designated HER1, is a 170 kDa transmembrane glycoprotein with a length of 1186 amino acids. It is identical with a previously described glycoprotein called SA-7 (species antigen 7). The extracellular receptor domain has a length of 621 amino acids, including 11 glycosylated asparagine residues and 51 cysteine residues. This domain contains the EGF binding site and also binds mammalian TGF-alpha.

Recombinant Rat EGF

Z300049 1.0 mg
EUR 480
Description: Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. This protein shows both strong sequential and functional homology with human type-alpha transforming growth factor (hTGF alpha), which is a competitor for EGF receptor sites. EGF receptors are expressed in almost all types of tissues. Parietal endoderm, mature skeletal muscles, and hematopoietic tissues do not express the receptor. The EGF receptor, designated HER1, is a 170 kDa transmembrane glycoprotein with a length of 1186 amino acids. It is identical with a previously described glycoprotein called SA-7 (species antigen 7). The extracellular receptor domain has a length of 621 amino acids, including 11 glycosylated asparagine residues and 51 cysteine residues. This domain contains the EGF binding site and also binds mammalian TGF-alpha.

Recombinant Rat TNF

Z300065 20 µg
EUR 85
Description: TNF is secreted by macrophages, monocytes, neutrophils, T cells, natural killer cells following their stimulation by bacterial lipopolysaccharides. Cells expressing CD4 secrete TNF-alpha while CD8(+) cells secrete little or no TNF-alpha. Stimulated peripheral neutrophilic granulocytes but also unstimulated cells and also a number of transformed cell lines, astrocytes, microglial cells, smooth muscle cells, and fibroblasts also secrete TNF. Human milk also contains this factor. The synthesis of TNF-alpha is induced by many different stimuli including interferons, IL-2, GM-CSF, SP, Bradykinin, Immune complexes, inhibitors of cyclooxygenase and PAF (platelet activating factor). Human TNF-alpha is a non-glycosylated protein of 17 kDa and a length of 157 amino acids. Murine TNF-alpha is N-glycosylated. Homology with TNF-beta is approximately 30%. TNF-alpha forms dimers and trimers.

Recombinant Rat TNF

Z300067 100 µg
EUR 270
Description: TNF is secreted by macrophages, monocytes, neutrophils, T cells, natural killer cells following their stimulation by bacterial lipopolysaccharides. Cells expressing CD4 secrete TNF-alpha while CD8(+) cells secrete little or no TNF-alpha. Stimulated peripheral neutrophilic granulocytes but also unstimulated cells and also a number of transformed cell lines, astrocytes, microglial cells, smooth muscle cells, and fibroblasts also secrete TNF. Human milk also contains this factor. The synthesis of TNF-alpha is induced by many different stimuli including interferons, IL-2, GM-CSF, SP, Bradykinin, Immune complexes, inhibitors of cyclooxygenase and PAF (platelet activating factor). Human TNF-alpha is a non-glycosylated protein of 17 kDa and a length of 157 amino acids. Murine TNF-alpha is N-glycosylated. Homology with TNF-beta is approximately 30%. TNF-alpha forms dimers and trimers.

Recombinant Rat TNF

Z300069 1.0 mg
EUR 950
Description: TNF is secreted by macrophages, monocytes, neutrophils, T cells, natural killer cells following their stimulation by bacterial lipopolysaccharides. Cells expressing CD4 secrete TNF-alpha while CD8(+) cells secrete little or no TNF-alpha. Stimulated peripheral neutrophilic granulocytes but also unstimulated cells and also a number of transformed cell lines, astrocytes, microglial cells, smooth muscle cells, and fibroblasts also secrete TNF. Human milk also contains this factor. The synthesis of TNF-alpha is induced by many different stimuli including interferons, IL-2, GM-CSF, SP, Bradykinin, Immune complexes, inhibitors of cyclooxygenase and PAF (platelet activating factor). Human TNF-alpha is a non-glycosylated protein of 17 kDa and a length of 157 amino acids. Murine TNF-alpha is N-glycosylated. Homology with TNF-beta is approximately 30%. TNF-alpha forms dimers and trimers.

Recombinant Rat IL6

Z300085 10 µg
EUR 235
Description: IL-6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T cells and B lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL-6 after stimulation. IL-6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL-11, and CT-1. All known members of the IL-6 cytokine family induce hepatic expression of acute phase proteins. The IL-6 receptor is expressed on T cells, mitogen-activated B cells, peripheral monocytes and some macrophage and B cell derived tumor cell types. It is not expressed in resting B cells but in resting T cells. The IL-6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids. It has been designated CD126.

Recombinant Rat IL6

Z300089 1.0 mg
EUR 6900
Description: IL-6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T cells and B lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL-6 after stimulation. IL-6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL-11, and CT-1. All known members of the IL-6 cytokine family induce hepatic expression of acute phase proteins. The IL-6 receptor is expressed on T cells, mitogen-activated B cells, peripheral monocytes and some macrophage and B cell derived tumor cell types. It is not expressed in resting B cells but in resting T cells. The IL-6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids. It has been designated CD126.

Recombinant Rat IL5

Z300155 10 µg
EUR 235
Description: Interleukin-5 is a specific hematopoietic growth factor that is responsible for the growth and differentiation of eosinophils. IL-5 promotes the growth of immature hematopoietic progenitor cells BFU-E while it causes differentiation of CFU-E the proliferation of which is inhibited by IL-5. IL-5 strongly stimulates the proliferation, cell activation, and differentiation of eosinophils. B cells can be made responsive to IL-5 by treatment with suboptimal doses of IL-1. Interleukin-5 also promotes the generation of cytotoxic T cells from thymocytes. In thymocytes IL-5 induces the expression of high affinity IL-2 receptors. In contrast to human Interleukin-5, mouse IL-5 also acts on B cells. It induces the proliferation of pre-activated B cells and their differentiation. High affinity and low affinity receptors for IL-5 are expressed in all hematopoietic and lymphoid cells.The low affinity receptor, CD125, has a molecular mass of 50 kDa (p60). The introduction of p60 into these cells generates a high affinity IL-5 receptor. The second subunit of the IL-5 receptor is identical with the larger subunit of the receptor for the colony stimulating factor GM-CSF (CD131). This subunit is involved also in the generation of a high affinity receptor for IL-3 and is being referred to as common beta.

Recombinant Rat IL5

Z300159 1.0 mg
EUR 6900
Description: Interleukin-5 is a specific hematopoietic growth factor that is responsible for the growth and differentiation of eosinophils. IL-5 promotes the growth of immature hematopoietic progenitor cells BFU-E while it causes differentiation of CFU-E the proliferation of which is inhibited by IL-5. IL-5 strongly stimulates the proliferation, cell activation, and differentiation of eosinophils. B cells can be made responsive to IL-5 by treatment with suboptimal doses of IL-1. Interleukin-5 also promotes the generation of cytotoxic T cells from thymocytes. In thymocytes IL-5 induces the expression of high affinity IL-2 receptors. In contrast to human Interleukin-5, mouse IL-5 also acts on B cells. It induces the proliferation of pre-activated B cells and their differentiation. High affinity and low affinity receptors for IL-5 are expressed in all hematopoietic and lymphoid cells.The low affinity receptor, CD125, has a molecular mass of 50 kDa (p60). The introduction of p60 into these cells generates a high affinity IL-5 receptor. The second subunit of the IL-5 receptor is identical with the larger subunit of the receptor for the colony stimulating factor GM-CSF (CD131). This subunit is involved also in the generation of a high affinity receptor for IL-3 and is being referred to as common beta.

Recombinant Rat IL2

Z300195 5 µg
EUR 60
Description: Rat IL2, also known as T-cell growth factor, is a secreted immunoregulatory cytokine produced by T-cells due to antigenic or mitogenic stimulation. IL2 binds to the IL2 receptor, which is found in T and B cells and natural killer cells, and is composed of three distinct components: the cytokine specific α-chain, and the β– and γc-subunits. Its receptor complex IL2 induces the proliferation of T cells, generation of cytotoxic T lymphocytes (CTLs), proliferation and synthesis of immunoglobulin by B cells, and the survival of natural killer cells. Its heterotrimeric receptor complex is also shared by Interleukin 4 (IL4) and Interleukin 7 (IL7) by its gamma chain, and receptor signalling is essential for its expression and differentiation of regulatory T cells in the immune response.

Recombinant Rat IL2

Z300197 100 µg
EUR 180
Description: Rat IL2, also known as T-cell growth factor, is a secreted immunoregulatory cytokine produced by T-cells due to antigenic or mitogenic stimulation. IL2 binds to the IL2 receptor, which is found in T and B cells and natural killer cells, and is composed of three distinct components: the cytokine specific α-chain, and the β– and γc-subunits. Its receptor complex IL2 induces the proliferation of T cells, generation of cytotoxic T lymphocytes (CTLs), proliferation and synthesis of immunoglobulin by B cells, and the survival of natural killer cells. Its heterotrimeric receptor complex is also shared by Interleukin 4 (IL4) and Interleukin 7 (IL7) by its gamma chain, and receptor signalling is essential for its expression and differentiation of regulatory T cells in the immune response.

Recombinant Rat IL2

Z300199 1.0 mg
EUR 1440
Description: Rat IL2, also known as T-cell growth factor, is a secreted immunoregulatory cytokine produced by T-cells due to antigenic or mitogenic stimulation. IL2 binds to the IL2 receptor, which is found in T and B cells and natural killer cells, and is composed of three distinct components: the cytokine specific α-chain, and the β– and γc-subunits. Its receptor complex IL2 induces the proliferation of T cells, generation of cytotoxic T lymphocytes (CTLs), proliferation and synthesis of immunoglobulin by B cells, and the survival of natural killer cells. Its heterotrimeric receptor complex is also shared by Interleukin 4 (IL4) and Interleukin 7 (IL7) by its gamma chain, and receptor signalling is essential for its expression and differentiation of regulatory T cells in the immune response.

Lypressin, (Recombinant)

22060535-1 5 mg
EUR 146.42

Recombinant Flagellin

TEOPP-0601 10ug Ask for price

Human Recombinant Humanp21 Recombinant Protein C-6 His Tag Lyophilized

IHUHUP21RC6HISLY50UG each
EUR 988
Description: Human Recombinant Humanp21 Recombinant Protein C-6 His Tag Lyophilized

Recombinant CA 242 Protein

VAng-Wyb8643-inquire inquire Ask for price
Description: CA 242 (Gastrointestinal Cancer), Calibrator Grade, recombinant protein from Cell Culture, 50466 Units/mL.

BAFF, rat recombinant

4453-100 each
EUR 927.6

BAFF, rat recombinant

4453-1000 each
EUR 6519.6

BAFF, rat recombinant

4453-20 each
EUR 314.4

CNTF, rat recombinant

4019-100 each
EUR 796.8

CNTF, rat recombinant

4019-1000 each
EUR 3974.4

CNTF, rat recombinant

4019-20 each
EUR 314.4

GDNF, rat recombinant

7157-10 each
EUR 333.6

GDNF, rat recombinant

7157-50 each
EUR 1358.4

MMP1, HEK (Recombinant)

20-abx073646
  • EUR 393.60
  • EUR 6991.20
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg
 KCNMB2-AS1 expression in NSCLC tissues and cells was detected utilizing reverse transcription-quantitative polymerase chain response. Cell proliferation, apoptosis, migration, and invasion have been evaluated utilizing Cell Counting Package-8, move cytometry, Transwell migration, and Transwell invasion assays, respectively. In vivo tumor xenograft fashions have been constructed to evaluate tumorigenicity. Bioinformatics predictions have been carried out to determine microRNAs concentrating on KCNMB2-AS1. Interactions between KCNMB2-AS1 and miR-374a-3p have been analyzed utilizing RNA immunoprecipitation, luciferase reporter, and rescue experiments.