August 26, 2020
Evaluation of RealStar Reverse Transcription-Polymerase Chain Reaction Kits
Analysis of RealStar Reverse Transcription-Polymerase Chain Response Kits for Filovirus Detection within the Laboratory and Area.
Prognosis of Ebola virus (EBOV) illness (EVD) requires laboratory testing.
The RealStar Filovirus Display screen reverse transcription-polymerase chain response (RT-PCR) equipment and the derived RealStar Zaire Ebolavirus RT-PCR equipment had been validated utilizing in vitro transcripts, supernatant of contaminated cell cultures, and medical specimens from sufferers with EVD.
The Filovirus Display screen equipment detected EBOV, Sudan virus, Taï Forest virus, Bundibugyo virus, Reston virus, and Marburg virus and differentiated between the genera Ebolavirus and Marburgvirus The quantity of filovirus RNA that might be detected with a likelihood of 95% ranged from 11 to 67 RNA copies/response on a LightCycler 480 II.
The Zaire Ebolavirus equipment is predicated on the Filovirus Display screen equipment however was optimized for detection of EBOV. It has an improved signal-to-noise ratio at low EBOV RNA concentrations and is considerably extra delicate than the Filovirus equipment. Each kits present considerably decrease analytical sensitivity on a SmartCycler II.
Scientific analysis revealed that the SmartCycler II, in contrast with different real-time PCR platforms, decreases the medical sensitivity of the Filovirus Display screen equipment to diagnose EVD at an early stage.
The Filovirus Display screen equipment detects all human-pathogenic filoviruses with good analytical sensitivity if carried out on an acceptable real-time PCR platform. Excessive analytical sensitivity is vital for early prognosis of EVD.

sebov-detection
human CD163 antigen,CD163 ELISA kit |
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YLA0098HU-48T | Shanghai YL Biotech | 48T | EUR 435 |
human CD163 antigen,CD163 ELISA kit |
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YLA0098HU-96T | Shanghai YL Biotech | 96T | EUR 562.5 |
Mouse Anti Human Cd163 Monoclonal Antibody |
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CABT-47162MH | Creative Diagnostics | 25 µg | EUR 446.4 |
Mouse Anti Human Cd163 Monoclonal Antibody |
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CABT-47163MH | Creative Diagnostics | 0.2 mg | EUR 1057.2 |
anti- CD163/M130 Antibody |
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FNab09771 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against CD163/M130 |
Anti-Hu CD163 PE |
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1P-645-T025 | ExBio | 25 tests | EUR 168 |
Anti-Hu CD163 PE |
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1P-645-T100 | ExBio | 100 tests | EUR 288 |
Anti-Hu CD163 APC |
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1A-645-T025 | ExBio | 25 tests | EUR 168 |
Anti-Hu CD163 APC |
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1A-645-T100 | ExBio | 100 tests | EUR 288 |
Anti-Hu CD163 Purified |
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11-645-C025 | ExBio | 0.025 mg | EUR 118.8 |
Anti-Hu CD163 Purified |
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11-645-C100 | ExBio | 0.1 mg | EUR 189.6 |
Human CD163 ELISA Kit |
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LF-EK50890 | Abfrontier | 1×96T | EUR 777.6 |
Human CD163 ELISA Kit |
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ELA-E1726h | Lifescience Market | 96 Tests | EUR 988.8 |
Human CD163 shRNA Plasmid |
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20-abx956176 | Abbexa |
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Anti-Hu CD163 PE-Cy7 |
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T7-645-T025 | ExBio | 25 tests | EUR 184.8 |
Anti-Hu CD163 PE-Cy7 |
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T7-645-T100 | ExBio | 100 tests | EUR 321.6 |
Anti-Hu CD163 PerCP-Cy5.5 |
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T9-645-T025 | ExBio | 25 tests | EUR 235.2 |
Anti-Hu CD163 PerCP-Cy5.5 |
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T9-645-T100 | ExBio | 100 tests | EUR 422.4 |
PE Anti-human CD163 Antibody *GHI/61* |
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116301K0 | AAT Bioquest | 25 tests | EUR 383 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PE Anti-human CD163 Antibody *GHI/61* |
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116301K1 | AAT Bioquest | 100 tests | EUR 995 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PE Anti-human CD163 Antibody *GHI/61* |
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116301K2 | AAT Bioquest | 500 tests | EUR 2984 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PE Anti-human CD163 Antibody *GHI/61* |
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116301K0-25tests | AAT Bioquest | 25 tests | EUR 383 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PE Anti-human CD163 Antibody *GHI/61* |
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116301K1-100tests | AAT Bioquest | 100 tests | EUR 995 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PE Anti-human CD163 Antibody *GHI/61* |
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116301K2-500tests | AAT Bioquest | 500 tests | EUR 2984 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
APC Anti-human CD163 Antibody *GHI/61* |
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116301B0 | AAT Bioquest | 25 tests | EUR 383 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
APC Anti-human CD163 Antibody *GHI/61* |
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116301B1 | AAT Bioquest | 100 tests | EUR 995 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
APC Anti-human CD163 Antibody *GHI/61* |
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116301B2 | AAT Bioquest | 500 tests | EUR 2984 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
APC Anti-human CD163 Antibody *GHI/61* |
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116301B0-25tests | AAT Bioquest | 25 tests | EUR 383 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
APC Anti-human CD163 Antibody *GHI/61* |
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116301B1-100tests | AAT Bioquest | 100 tests | EUR 995 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
APC Anti-human CD163 Antibody *GHI/61* |
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116301B2-500tests | AAT Bioquest | 500 tests | EUR 2984 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
FITC Anti-human CD163 Antibody *GHI/61* |
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116301G0 | AAT Bioquest | 100 tests | EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
FITC Anti-human CD163 Antibody *GHI/61* |
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116301G1 | AAT Bioquest | 500 tests | EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
FITC Anti-human CD163 Antibody *GHI/61* |
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116301G0-100tests | AAT Bioquest | 100 tests | EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
FITC Anti-human CD163 Antibody *GHI/61* |
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116301G1-500tests | AAT Bioquest | 500 tests | EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
TRITC Anti-human CD163 Antibody *GHI/61* |
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116301H0 | AAT Bioquest | 100 tests | EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
TRITC Anti-human CD163 Antibody *GHI/61* |
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116301H1 | AAT Bioquest | 500 tests | EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PerCP Anti-human CD163 Antibody *GHI/61* |
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116301S0 | AAT Bioquest | 25 tests | EUR 383 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PerCP Anti-human CD163 Antibody *GHI/61* |
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116301S1 | AAT Bioquest | 100 tests | EUR 995 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PerCP Anti-human CD163 Antibody *GHI/61* |
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116301S2 | AAT Bioquest | 500 tests | EUR 2984 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
TRITC Anti-human CD163 Antibody *GHI/61* |
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116301H0-100tests | AAT Bioquest | 100 tests | EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
TRITC Anti-human CD163 Antibody *GHI/61* |
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116301H1-500tests | AAT Bioquest | 500 tests | EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PerCP Anti-human CD163 Antibody *GHI/61* |
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116301S0-25tests | AAT Bioquest | 25 tests | EUR 383 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PerCP Anti-human CD163 Antibody *GHI/61* |
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116301S1-100tests | AAT Bioquest | 100 tests | EUR 995 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PerCP Anti-human CD163 Antibody *GHI/61* |
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116301S2-500tests | AAT Bioquest | 500 tests | EUR 2984 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacBlue Anti-human CD163 Antibody *GHI/61* |
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116301I0 | AAT Bioquest | 100 tests | EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacBlue Anti-human CD163 Antibody *GHI/61* |
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116301I1 | AAT Bioquest | 500 tests | EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacBlue Anti-human CD163 Antibody *GHI/61* |
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116301I0-100tests | AAT Bioquest | 100 tests | EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacBlue Anti-human CD163 Antibody *GHI/61* |
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116301I1-500tests | AAT Bioquest | 500 tests | EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
Purified Anti-human CD163 Antibody *GHI/61* |
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11630000 | AAT Bioquest | 100 ug | EUR 365 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
Purified Anti-human CD163 Antibody *GHI/61* |
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11630000-100ug | AAT Bioquest | 100 ug | EUR 365 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacOrange Anti-human CD163 Antibody *GHI/61* |
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116301J0 | AAT Bioquest | 100 tests | EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacOrange Anti-human CD163 Antibody *GHI/61* |
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116301J1 | AAT Bioquest | 500 tests | EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacOrange Anti-human CD163 Antibody *GHI/61* |
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116301J0-100tests | AAT Bioquest | 100 tests | EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacOrange Anti-human CD163 Antibody *GHI/61* |
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116301J1-500tests | AAT Bioquest | 500 tests | EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
Human CellExp? CD163, Human recombinant |
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9226-10 | Biovision | each | EUR 366 |
Human CellExp? CD163, Human recombinant |
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9226-50 | Biovision | each | EUR 927.6 |
Canine CD163 antigen(CD163 LISA kit |
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GA-E0062CN-48T | GenAsia Biotech | 48T | EUR 482.4 |
Canine CD163 antigen(CD163 LISA kit |
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GA-E0062CN-96T | GenAsia Biotech | 96T | EUR 820.8 |
Porcine CD163 antigen,CD163 LISA kit |
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GA-E0045PC-48T | GenAsia Biotech | 48T | EUR 436.8 |
Porcine CD163 antigen,CD163 LISA kit |
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GA-E0045PC-96T | GenAsia Biotech | 96T | EUR 708 |
Porcine CD163 antigen,CD163 LISA kit |
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YLA0139PO-48T | Shanghai YL Biotech | 48T | EUR 502.5 |
Porcine CD163 antigen,CD163 LISA kit |
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YLA0139PO-96T | Shanghai YL Biotech | 96T | EUR 618.75 |
ELISA kit for Human CD163 |
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EK5296 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CD163 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Human CD163 PicoKine ELISA Kit |
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EK0715 | BosterBio | 96 wells | EUR 510 |
Description: For quantitative detection of human CD163 in cell culture supernates, serum and plasma(heparin). |
CD163 Antibody |
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20-abx242956 | Abbexa |
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CD163 antibody |
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10R-6496 | Fitzgerald | 100 ug | EUR 243.6 |
Description: Mouse monoclonal CD163 antibody |
CD163 antibody |
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10R-CD163aRT | Fitzgerald | 250 ug | EUR 859.2 |
Description: Mouse monoclonal CD163 antibody |
CD163 Antibody |
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37157-100ul | SAB | 100ul | EUR 302.4 |
CD163 Antibody |
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49553-100ul | SAB | 100ul | EUR 399.6 |
CD163 Antibody |
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49553-50ul | SAB | 50ul | EUR 286.8 |
CD163 Antibody |
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ABD8235 | Lifescience Market | 100 ug | EUR 525.6 |
CD163 Antibody |
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DF8235 | Affbiotech | 200ul | EUR 420 |
CD163 Antibody |
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1-CSB-PA969205 | Cusabio |
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Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100 |
CD163 Antibody |
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1-CSB-PA801238LA01HU | Cusabio |
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Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200 |
Cd163 Antibody |
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1-CSB-PA650452LA01MO | Cusabio |
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Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000 |
CD163 Antibody |
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F50316-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 322.15 |
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. |
CD163 Antibody |
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F50316-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. |
CD163 Antibody |
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RQ4259 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
CD163 Antibody |
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R30973 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: CD163 (Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptor for the hemoglobin-haptoglobincomplex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the CD163 gene to chromosome 12p13.3. Specific CD163-mediated endocytosis of haptoglobin-hemoglobin complexes was measurable in cells transfected with CD163 cDNA and in CD163-expressing myelomonocytic lymphoma cells.CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by anti-CD163 antibodies. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells. |
CD163 Antibody |
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R30974 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: Cluster of Differentiation 163, also known as Hemoglobin scavenger receptor, is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptorfor the hemoglobin-haptoglobin complex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the gene to chromosome 12p13.3. CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by CD163 antibody. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells. |
CD163 Antibody |
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V3937-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V3937-20UG | NSJ Bioreagents | 20 ug | EUR 153.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V3937SAF-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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R20390-0.1ML | NSJ Bioreagents | 100ul | EUR 409 |
CD163 Antibody |
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V7470-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V7470-20UG | NSJ Bioreagents | 20 ug | EUR 153.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V7470IHC-7ML | NSJ Bioreagents | 7 ml | EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V7470SAF-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V8227-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V8227-20UG | NSJ Bioreagents | 20 ug | EUR 153.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V8227SAF-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V8415-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
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V8415-20UG | NSJ Bioreagents | 20 ug | EUR 153.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
Analysis of Ebola Virus Inhibitors for Drug Repurposing.
A systematic display of FDA-approved medicine was carried out to establish compounds with in vitro antiviral actions in opposition to Ebola virus (EBOV). Compounds lively (>50% viral inhibition and <30% mobile toxicity) at a single focus had been examined in dose-response assays to quantitate the antiviral actions in replication and viral entry assays in addition to cytotoxicity within the Vero cell line used to conduct these assays.
On the idea of the accepted human dosing, toxicity/tolerability, and pharmacokinetic knowledge, seven of those in vitro hits from completely different pharmacological lessons (chloroquine (CQ), amiodarone, prochlorperazine, benztropine, azithromycin, chlortetracycline, and clomiphene) had been evaluated for his or her in vivo efficacy at a single dose and had been administered by way of both intraperitoneal (ip) or oral route.
Initially, azithromycin (100 mg/kg, twice day by day, ip), CQ (90 mg/kg, twice day by day, ip), and amiodarone (60 mg/kg, twice day by day, ip) demonstrated vital will increase in survival within the mouse mannequin. After repeat analysis, solely CQ was discovered to reproducibly give vital efficacy within the mouse mannequin with this dosing routine.
Azithromycin and CQ had been additionally examined in a guinea pig mannequin of EBOV an infection over a variety of doses, however not one of the doses elevated survival, and drug-related toxicity was noticed at decrease doses than within the mouse. These outcomes present the advantages and particular challenges related to drug repurposing and spotlight the necessity for cautious analysis of accepted medicine as quickly deployable countermeasures in opposition to future pandemics.