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EnDuo, a novel derivative of Endostar, inhibits the migration of colon cancer cells, suppresses matrix metalloproteinase-2/9 expression and impedes AKT/ERK activation
Background/goals: Colon most cancers stays a life-threating illness with rising morbidity and mortality worldwide regardless of the development in trendy medical remedy. Subsequently, novel and efficient anti-colon cancers medicine are urgently wanted. On this research, we investigated the anti-metastatic property EnDuo, a modified model of Endostar, and the underlying mechanisms. Strategies: Colon most cancers cells had been handled with completely different concentrations of EnDuo (50 μg/mL, 100 […]